The real estate division is responsible for administering The Real Estate Brokers Act and The Mortgage Brokers Act. This division registers real estate brokers, salespersons, and mortgage brokers, monitors brokers' trust accounts, and investigates complaints against real estate brokers, salespersons and mortgage brokers.

The Real Estate Advisory Committee established by Manitoba Regulation 593/88 under The Real Estate Brokers Act recommends real estate projects to the Commission for funding from the interest the Commission receives from real estate brokers' trust accounts.

The Real Estate Advisory Council is a non-statutory body established by The Manitoba Securities Commission and The Manitoba Real Estate Association (MREA) to advise and make recommendations to the Commission and MREA on real estate issues; to consider mutually beneficial ideas, policies or legislative reform; and give advance notice of trends or developments in the real estate industry.